Erik Morales Mejías

Formación Académica

• Magíster en Educación Superior en Ciencias de la Salud
• Máster en Oncología Molecular
• Médico Cirujano Especialista en Anatomía Patológica

Publicaciones / Artículos

• Dominique Scherer, Carol Barahona Ponce, Claudio Mengoa, Paola Montenegro, Hector Losada, Ana Lineth García, Armando Rojas, Erik Morales (+23 coauthors). Data Resource Profile: EULAT Eradicate GBC: the European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer. International Journal of Epidemiology, 2025, 54, 1–8.
• Felix Boekstegers, Carol Barahona Ponce, Erik Morales (+23 coauthors …). Gallbladder Cancer and Dysplasia in Cholecystectomy Specimens: A Large Study in High-Incidence Regions of South America. Clin Gastroenterol Hepatol 2025 Aug;23 (9):1535-1545.e7.
• Constanza Gonzalez, Alfonso García-Pérez, Bruno Nervi, César Muñoz, Erik Morales (+ 5 coauthors). Cholecystectomy and digestive cancer in Chile: Complementary results from interrupted time series and aggregated data analyses. Int. J. Cancer. 2025;156:91 –103.
• Francisco Ceballos, Felix Boekstegers, Dominique Scherer, Carol Barahona Ponce, Katherine Marcelain, Valentina Gárate-Calderón, Melanie Waldenberger, Erik Morales (+ 27 coauthors). Inbreeding and Gallbladder Cancer Risk - Homozygosity Associations Adjusted for Indigenous American Ancestry, BMI, and Genetic Risk of Gallstone Disease. Cancers 2024, 16, 4195
• Felix Boekstegers, Dominique Scherer , Carol Barahona Ponce, Katherine Marcelain, Valentina Gárate-Calderón, Melanie Waldenberger, Erik Morales (+ 32 coauthors).  Development and internal validation of a multifactorial risk prediction model for gallbladder cancer in a high-incidence country. Int. J. Cancer. 2023;153:1151–1161
• Linda Zollner, Felix Boekstegers , Carol Barahona Ponce, Dominique Scherer, Katherine Marcelain, Valentina Gárate-Calderón, Melanie Waldenberger, Erik Morales (+ 36 coauthors). Gallbladder Cancer Risk and Indigenous South American Mapuche Ancestry: Instrumental Variable Analysis Using Ancestry-Informative Markers  Cancers 2023, 15, 4033
• Sergio Sotelo, Carlos Manterola, Tamara Otzen, Erik Morales, Iván Castillo. Prevalence of Gastric Preneoplastic Lesions in First-Degree Relatives of Patients with Gastric Cancer: a Cross-Sectional Study. J Gastrointest Cancer. 2022 Apr 30. doi: 10.1007/s12029-022-00827-x
• Alice Blandino, Dominique Scherer, Trine B Rounge, Sinan U Umu, Felix Boekstegers, Carol Barahona Ponce, Katherine Marcelain, Valentina Gárate-Calderón, Melanie Waldenberger, Erik Morales (+ 31 coauthors). Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression. Cancers (Basel) 2022 Jan 27; 14 (3):634. doi: 10.3390/cancers 14030634.
• Rojas A, Lindner C, Schneider I, Gonzàlez I, Araya H, Morales E (+ 4 coauthors). Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer. World J Gastrointest Oncol 2021; 13(12): 1997-2012 [PMID: 35070037 DOI: 10.4251/wjgo.v13.i12.1997.
• Salvo, M.; González-Feliú, E.; Toro, J.; Gallegos, I.; Maureira, I.; Miranda-González, N.; Barajas, O.; Bustamante, E.; Ahumada, M.; Colombo, A.; Armisén, R.; Villamán, C.; Ibañez, C.; Bravo, M.L.; Sanhueza, V.; Spencer, M.L.; de Toro, G.; Morales, E (+ 7 coauthors). Validation of an NGS Panel Designed for Detection of Actionable Mutations in Tumors Common in Latin America. J. Pers. Med. 2021, 11, 899. https://doi.org/10.3390/jpm11090899.
• Barahona Ponce C, Scherer D, Brinster R, Boekstegers F, Marcelain K, Gárate V, Müller B, de Toro G, Retamales J, Barajas O, Ahumada M, Morales E (+ 36 coauthors). J. Gallstones, Body Mass Index, C-reactive Protein and Gallbladder Cancer - Mendelian Randomization Analysis of Chilean and European Genotype Data. Hepatology. 2021 May; 73 (5):1783-1796. doi: 10.1002/hep.31537. PMID: 32893372.
• Rojas A., Araya P, Gonzalez I. And Morales E. Gastric Tumor Microenvironment. Advances in Experimental Medicine and Biology (2020): 1226, 23-35. Tumor Microenvironments in Organs: Vol. One. Springer Nature Switzerland AG 2020.
• Boekstegers F, Marcelain K, Barahona Ponce C, Baez Benavides PF, Müller B, de Toro G, Retamales J, Barajas O, Ahumada M, Morales E (+ 36 coauthors). ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans. Cancer Epidemiol. 2020 Apr; 65:101643. doi: 10.1016/j.canep.2019.101643. Epub 2020 Feb 10. PMID: 32058310.
• Brägelmann J, Barahona Ponce C, Marcelain K, Roessler S, Goeppert B, Gallegos I, Colombo A, Sanhueza V, Morales E (+ 14 coauthors). Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder cancer. Hepatology (Baltimore, Md.). 2020 Oct 5; [PubMed PMID: 33020926]. DOI: 10.1002/hep.31585.
• Muñoz C, Marino C, and Morales E. Total laparoscopic radical cholecystectomy (lymphadenectomy and hepatic resection of segments IVb-V) after incidental gallbladder carcinoma (with video). Journal of Visceral Surgery (2018), https://doi.org/10.1016/j.jviscsurg.
• Añazco C, Delgado-López F, Araya P, González I, Morales E, Pérez-Castro R, Romero J, Rojas A. Lysyl oxidase isoforms in gastric cancer. Biomark Med. 2016 Sep; 10(9):987-98. doi: 10.2217/bmm-2016-0075. Electronic publication of August 26, 2016.
• Rojas A, Delgado-López F, Pérez-Castro R, González I, Romero J, Rojas I, Araya P, Añazco C, Morales E, Llanos J. HMGB1 enhances the protumoral activities of M2 macrophages through a RAGE-dependent mechanism. Biol tumoral. March 2016; 37(3):3321-9. doi: 10.1007/s13277-015-3940-y.

Redes Científicas

• Sociedad Chilena de Anatomía Patológica
• Comité de Anatomía Patológica de la Comisión Nacional de Acreditación de Especialidades Médicas (CONACEM)