Ángel Gabriel Cayo Nuñez

Departamento de Medicina Traslacional – Facultad de Medicina UCM

Línea de investigación: Senescencia celular y biología molecular del cáncer (Gástrico, mamario y colorrectal) por el uso de quimioterapéuticos.

Grado académico:

• Profesor de Ciencias con mención en Biología, Universidad Católica del Maule
• Magíster en Ciencias con mención en Microbiología, Universidad Austral de Chile
• Doctor en Ciencias Biomédicas Universidad de Talca

Publicaciones y Artículos:

• 2025 - Extracellular vesicles (EVs) derived from senescent endothelial cells promote platelet activation. 
• 2023 - Palbociclib- Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy  
• 2022 - Selective TASK-1 Inhibitor with a Defined Structure- Activity Relationship Reduces Cancer Cell Proliferation and Viability  
• 2022 - Potassium Channels as a Target for Cancer Therapy: Current Perspectives  
• 2022 - Platelets, a Key Cell in Inflammation and Atherosclerosis Progression  
• 2022 - Two New Adenosine Derivatives and their Antiproliferative. DOI: 10.2174/1871520621666210528151818. 
• 2021 - mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership . DOI: 10.3390/ijms22158149.
• 2021 - Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3 . DOI: 10.3390/ijms21093287.
• 2020 - Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro. DOI: 10.3390/ijms21093287. 
• 2019 - SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells . DOI: 10.3390/ijms20215292.